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  • IgG Depleted Single Donor Human Serum Heat Inactivated

IgG Depleted Single Donor Human Serum Heat Inactivated

Human serum from individual donor units is depleted of IgG antibodies, 0.2 micron filtered, aliquoted, heat-inactivated, and frozen.
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Specifications
Single Donor
Frozen Liquid
-70°C or below
Assay development & validation, Immunoassays, In vitro diagnostics, Non-clinical & preclinical studies, R&D, Vaccine development
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Bulk Requirements for Human Serum
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 $2,100.00
Lead time on this item is currently: 2-4 Weeks

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Product Overview
Product Overview
Application: Assay development & validation, Immunoassays, In vitro diagnostics, Non-clinical & preclinical studies, R&D, Vaccine development
Storage Conditions: -70°C or below
Shipping Conditions: Dry ice
Species: Human
Application Notes: Suitable for sample dilution, immunoassays, control serum, and various applications requiring serum supplementation.
Guarantee: Product quality is guaranteed to meet Pel-Freez Biologicals’ specifications for 1 year from the date of receipt by the customer as long as the product is stored in accordance with the indicated storage conditions.
Testing: CH50: Negative Residual IgG: <10% Serum tested negative for infectious disease per FDA guidelines.
Packaging: Cryovial, Poly bottle
Product Attributes: Antibody Depleted, Heat Inactivated, Off-the-Clot (OTC)
Donor Sex: Either
Donor Type: Single Donor
Product Types: Serum
Physical State: Frozen Liquid
Depletion Process: IgG Depleted
Source: OTC Serum
Product Applications
  • Assay development & validation
  • Immunoassays
  • In vitro diagnostics
  • Opsonophagocytic assay
  • R&D
  • Serum bactericidal assay
  • Toxicology assays
  • Vaccine development

Product References

Salic acid protects nontypeable Haemophilus influenza from natural IgM and promotes survival in murine respiratory tract.

Jackson, M. D., Wong, S. M. & Akerley, B. J. Sialic acid protects nontypeable haemophilus influenzae from natural igm and promotes survival in murine respiratory tract. Infect. Immun. 89, (2021).
Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae

Shaughnessy, J. et al. Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae. Front. Immunol. 11, 2680 (2020).
Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection

Parzych, E. M. et al. Synthetic dna delivery of an optimized and engineered monoclonal antibody provides rapid and prolonged protection against experimental gonococcal infection. MBio 12, 1–13 (2021).
Neisseria meningitidis urethritis outbreak isolates express a novel factor H binding protein variant that is a potential target of group B-directed meningococcal (MenB) …

Tzeng, Y. L. et al. Neisseria meningitidis urethritis outbreak isolates express a novel factor H binding protein variant that is a potential target of group B-Directed meningococcal (menb) vaccines. Infect. Immun. 88, (2020).
Vaccination with Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model

Fernandez, J. et al. Vaccination with Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model . J. Infect. Dis. (2021).
Preclinical efficacy of a lipooligosaccharide peptide mimic candidate gonococcal vaccine

Gulati, S. et al. Preclinical efficacy of a lipooligosaccharide peptide mimic candidate Gonococcal vaccine. MBio 10, (2019).
Complement-Dependent Serum Bactericidal Assays for Neisseria gonorrhoeae

Gulati, S., Rice, P. A. & Ram, S. Complement-Dependent Serum Bactericidal Assays for Neisseria gonorrhoeae. in Methods in Molecular Biology vol. 1997 267–280 (Humana Press Inc., 2019).
Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria

Shaughnessy, J. et al. Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae. Front. Immunol. 11, (2020).