Rabbit Anti-TDP43
Affinity purified rabbit polyclonal antibody to human and rat TDP43.
Specifications
Physical State:
Liquid
Storage:
-20°C or -80°C (long term), 2 – 8°C (short term)
Buffer:
Learn more PBS, 30% glycerol
Lead time on this item is currently: 2-4 Weeks
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Product Overview
| Host Species: | Rabbit |
|---|---|
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide C-terminal to the caspase-cleavage site (between D219 and V220) of human TDP-43. |
| Immunogen Species: | Human |
| Species Reactivity: | Human, Rat |
| Gene Name: | TARDBP |
| Molecular Weight: | 43 kDa |
| RRID: | AB_2492258 |
| Purification: | Affinity-purified |
| Physical State: | Liquid |
| Buffer: | PBS, 30% glycerol |
| Specificity: | Recognizes endogenous ~43 kDa TDP-43 protein in Western blots of rat brain lysate. Expected molecular weight is dependent upon the TDP-43 species present in sample (full-length vs. truncated TDP-43). Under non-denaturing conditions (for example, by IHC), this antibody detects TDP-43 inclusions in human brain tissue with TDP-43 proteinopathy, but does not detect full-length nuclear TDP-43. Under denaturing conditions (for example, by Western Blot analysis) this antibody detects the C-terminus of full-length and truncated human TDP-43. |
| Application Notes: | Recommended starting dilutions: WB 1:1000; WB Brain 1:1000; IHC 1:250 – 1:1000; ICC 1:1000. |
| Testing: | Western blot on every lot. |
| Storage Conditions: | -20°C or -80°C (long term), 2 – 8°C (short term) |
| Handling: | Aliquot on receipt to avoid repeated freeze-thaw cycles. Keep a working aliquot at 2 – 8°C for short-term use. |
| Shipping Conditions: | Dry ice |
| Expiration: | Stable for at least 1 year from receipt when stored at -20°C. |
Product Applications
- Western blot
- Immunohistochemistry
- Immunofluorescence (IF/ICC)
- Neuroscience research