Rabbit Anti-P-TRPM7 (Ser1493)
Antigen affinity purified rabbit polyclonal antibody to human TRPM7 (Ser-1493).
Specifications
Physical State:
Liquid
Storage:
-20°C
Buffer:
Learn more PBS, 1 mg/mL BSA, 0.05% sodium azide, 50% glycerol
Lead time on this item is currently: 2-4 Weeks
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Product Overview
| Host Species: | Rabbit |
|---|---|
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Immunogen: | Phospho-TRPM7 (Ser-1493) synthetic peptide (conjugated to carrier) matching residues around Ser-1493 in human TRPM7. This site is conserved in rat and mouse TRPM7, but the homology around the site is low. This site has no homology to other TRPM family members. |
| Immunogen Species: | Human |
| Species Reactivity: | Human |
| Gene Name: | TRPM7 |
| Molecular Weight: | 220 |
| Purification: | Antigen affinity-purified |
| Physical State: | Liquid |
| Buffer: | PBS, 1 mg/mL BSA, 0.05% sodium azide, 50% glycerol |
| Specificity: | The antibody was cross-adsorbed to unphosphorylated TRPM7 (Ser-1493) then affinity purified using phospho-TRPM7 (Ser-1493) peptide. This antibody detects a 220 kDa* protein on Western blots of human MDA-MB-231 cells stimulated with calyculin A, and detects a 70 kDa autophosphorylated recombinant kinase domain of human TRPM7. These reactivities are not observed after lambda phosphatase treatment to dephosphorylate TRPM7. |
| Application Notes: | Recommended starting dilution: WB 1:500. |
| Testing: | Western blot on every lot. |
| Storage Conditions: | -20°C |
| Handling: | Supplied in 50% glycerol, so aliquots can be drawn at -20°C without thawing the stock. |
| Shipping Conditions: | Dry ice |
| Expiration: | Stable for at least 1 year from receipt when stored at -20°C. |
Product Applications
- Western blot
- Neuroscience research