Mouse Anti-P-GSK-3α/β (Tyr279/Tyr216)
Protein A purified mouse monoclonal antibody to human, mouse and rat GSK-3α/β (Tyr-279/Tyr-216).
Specifications
Physical State:
Liquid
Storage:
-20°C
Buffer:
Learn more PBS, 1 mg/mL BSA, 0.05% sodium azide, 50% glycerol
Lead time on this item is currently: 2-4 Weeks
Need help? Ask a Specialist Contact UsOR +1 (800) 643-3426
Product Overview
| Host Species: | Mouse |
|---|---|
| Clonality: | Monoclonal |
| Clone: | M132 |
| Isotype: | IgG1 |
| Immunogen: | Clone M132 was generated from a phospho-GSK-3β (Tyr-216) synthetic peptide (conjugated to KLH) matching residues around tyrosine 216 of human GSK-3β. This peptide sequence is also found in GSK-3α (Tyr-279) and is highly conserved in GSK-3 genes in rat and mouse. |
| Immunogen Species: | Human |
| Species Reactivity: | Human, Mouse, Rat |
| Gene Name: | GSK3A/B |
| Molecular Weight: | 46/50 |
| Purification: | Protein A-purified |
| Physical State: | Liquid |
| Buffer: | PBS, 1 mg/mL BSA, 0.05% sodium azide, 50% glycerol |
| Specificity: | Detects 46/50 kDa* proteins matching the apparent molecular mass of GSK-3β and GSK-3α on Western blots of pervanadate treated rabbit fibroblasts, as well as treated human SKN-SH and A431 cells. |
| Application Notes: | Recommended starting dilution: WB 1:1000. |
| Testing: | Western blot on every lot. |
| Storage Conditions: | -20°C |
| Handling: | Supplied in 50% glycerol, so aliquots can be drawn at -20°C without thawing the stock. |
| Shipping Conditions: | Dry ice |
| Expiration: | Stable for at least 1 year from receipt when stored at -20°C. |
Product Applications
- Western blot
- Cancer research