Publications

A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry

Caprioli et al. (2014). Journal of Mass Spectrometry. doi: 10.1002/jms.3411

…d MALDI matrices including α-cyano-4- hydroxycinnamic acid (CHCA) and trans-ferulic acid (FA), as well as trifluoroacetic acid (TFA), were obtained from Sigma-Aldrich. Fresh-frozen tissue samples (pig adrenal gland and rat brain) were obtained frozen on dry ice from Pel-Freez Biologicals (Rogers, AR), and subsequently stored at −80°C until use. Pretreatment of MALDI Plates with CHCA for Analysi