JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

IgG Depleted Single Donor Human Complement

IgG Depleted Single Donor Human Complement

Human serum is depleted of IgG antibodies, 0.2 micron filtered, aliquoted and frozen.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Specifications

Donor Type: Single

Physical State: Frozen liquid

Storage: -70°C or below

Applications: Assay Development & Validation, Vaccine Development, Non-Clinical & Preclinical Studies

Learn more

Size:

Product Code: Select size

Quantity:

Custom/Bulk request

Bulk Requirements for Human Serum

More 1 L

From
$30.00

Lead time on this item is currently: 2-4 Weeks

Need help? Ask a Specialist Contact Us OR +1 (800) 643-3426

Product Overview

Product Overview
Application:	Assay Development & Validation, Vaccine Development, Non-Clinical & Preclinical Studies
Storage Conditions:	-70°C or below
Shipping Conditions:	Dry ice
Species:	Human
Application Notes:	Suitable for functional antibody assays (SBA-Serum Bactericidal Assay, MOPA/OPA- Multiplexed /Opsonophagocytic Killing Assay) for vaccine evaluation. Complement components are extremely heat-sensitive; for best results, thaw complement on ice or in a cold water bath. Aliquots may be made and frozen at -70°C or below. Avoid multiple freeze-thaw cycles. When a working aliquot is thawed, do not re-freeze remaining complement, but discard it.
Guarantee:	Product quality is guaranteed to meet Pel-Freez Biologicals’ specifications for 1 year from the date of receipt by the customer as long as the product is stored in accordance with the indicated storage conditions.
Testing:	CH50: Report Residual IgG: <10% Serum tested negative for infectious disease per FDA guidelines.
Product Attributes:	Complement
Packaging:	Poly bottle
Donor Sex:	Either
Product Types:	Complement
Donor Type:	Single

Product Applications

Assay development & validation
Vaccine development
Serum bactericidal assay
Opsonophagocytic assay

Product References

Salic acid protects nontypeable Haemophilus influenza from natural IgM and promotes survival in murine respiratory tract.
Jackson, M. D., Wong, S. M. & Akerley, B. J. Sialic acid protects nontypeable haemophilus influenzae from natural igm and promotes survival in murine respiratory tract. Infect. Immun. 89, (2021).

Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae
Shaughnessy, J. et al. Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae. Front. Immunol. 11, 2680 (2020).

Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection
Parzych, E. M. et al. Synthetic dna delivery of an optimized and engineered monoclonal antibody provides rapid and prolonged protection against experimental gonococcal infection. MBio 12, 1–13 (2021).

Neisseria meningitidis urethritis outbreak isolates express a novel factor H binding protein variant that is a potential target of group B-directed meningococcal (MenB) …
Tzeng, Y. L. et al. Neisseria meningitidis urethritis outbreak isolates express a novel factor H binding protein variant that is a potential target of group B-Directed meningococcal (menb) vaccines. Infect. Immun. 88, (2020).

Vaccination with Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model
Fernandez, J. et al. Vaccination with Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model . J. Infect. Dis. (2021).

Preclinical efficacy of a lipooligosaccharide peptide mimic candidate gonococcal vaccine
Gulati, S. et al. Preclinical efficacy of a lipooligosaccharide peptide mimic candidate Gonococcal vaccine. MBio 10, (2019).

Complement-Dependent Serum Bactericidal Assays for Neisseria gonorrhoeae
Gulati, S., Rice, P. A. & Ram, S. Complement-Dependent Serum Bactericidal Assays for Neisseria gonorrhoeae. in Methods in Molecular Biology vol. 1997 267–280 (Humana Press Inc., 2019).

Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria
Shaughnessy, J. et al. Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae. Front. Immunol. 11, (2020).