Custom service
Custom antibody and antiserum production
US-based custom polyclonal antibody and antiserum production in New Zealand White rabbits. You supply the antigen; we run the standard 9-week protocol under USDA licensure and IACUC review and deliver terminal antiserum with full QC documentation.
Custom antibody services you can rely on
We produce high-quality rabbit custom polyclonal antibodies and antiserum through controlled immunization protocols to provide the reliability and flexibility your research depends on.
Choose our standard polyclonal antiserum service with full QC traceability, or add optional downstream services, including ELISA testing, affinity purification, IgG fractionation, Protein A purification, and more.
Process Overview
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Discuss your project requirements
Outline your research goals with our team to create a custom antibody production plan.
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Send us your antigen
Ship your antigen using our simple submission process for secure, tracked handling.
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Production & quality testing
Immunization and QC testing are performed under strict IACUC and USDA oversight.
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Delivery to your lab
Receive your antibodies with full QC documentation and shipment traceability.
Standard protocol
A 9-week schedule you can plan around
Our standard rabbit immunization schedule delivers consistent antiserum and predictable timelines. Every phase, from acclimation to final collection, is monitored daily by experienced staff and overseen by our Attending Veterinarian. The schedule can be adjusted to your study.
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Day -6Week 0
Acclimation and quarantine
Animals settle in for at least six days before any procedure.
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Day 1Week 1
Pre-immune bleed and primary immunization
A pre-immunization serum sample is collected before the first dose.
2 weeks of daily health checks only
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Day 21Week 4
Primary bleed and booster 1
Serum from the primary response is collected as the first booster is given.
2 weeks of daily health checks only
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Day 42Week 7
Booster 1 bleed and booster 2
Serum from booster 1 is collected as the second booster is given.
1 week of daily health checks only
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Day 56Week 9
Terminal collection
Exsanguination yields the terminal antiserum, dispensed to your specifications and frozen at –80 °C.
View the full week-by-week schedule
| Week | Day | Activity |
|---|---|---|
| 0 | -6 | Acclimation and quarantine Animals settle in for at least six days before any procedure. |
| 1 | 1 | Pre-immune bleed and primary immunization A pre-immunization serum sample is collected before the first dose. |
| 2 | 7 | Health check only (no procedures) |
| 3 | 14 | Health check only (no procedures) |
| 4 | 21 | Primary bleed and booster 1 Serum from the primary response is collected as the first booster is given. |
| 5 | 28 | Health check only (no procedures) |
| 6 | 35 | Health check only (no procedures) |
| 7 | 42 | Booster 1 bleed and booster 2 Serum from booster 1 is collected as the second booster is given. |
| 8 | 49 | Health check only (no procedures) |
| 9 | 56 | Terminal collection Exsanguination yields the terminal antiserum, dispensed to your specifications and frozen at –80 °C. |
On-site care, every day of the protocol
Animals settle in for at least six days before any procedure. Every phase, from acclimation to final collection, is monitored daily by experienced staff and overseen by our Attending Veterinarian under USDA Animal Care licensure and IACUC review.
The same welfare standards that govern our farms apply to custom antibody animals. See our animal welfare page for certifications and sourcing practices.
Custom antibody and antiserum service outputs
The primary output of our custom antibody and antiserum production is high-quality terminal antiserum. Terminal antiserum is collected at the end of the immunization schedule, dispensed to your specifications, and frozen at –80 °C for long-term stability.
Intermittent serum samples, whole blood for PBMC isolation, and additional services, such as ELISA or antibody purification, can be arranged upon request.
Should I store antibodies at -20°C or -80°C, and should I aliquot them on delivery?
What is your standard protocol for custom polyclonal antibodies and antiserum?
The standard 9-week schedule includes acclimation, a primary immunization, two boosters, and a final bleed for terminal antiserum collection. The client provides the antigens, with adjuvants and positive or negative controls available upon request.
Do you offer antigen design or purification?
Can you modify the standard immunization schedule?
Do you provide ELISA results with all projects?
How is animal welfare monitored during custom antibody and antiserum production?
Have specific antibody or antiserum needs? We can help.
Send us your project requirements and a scientist replies with a plan and a quotation, or start with a short conversation.