Evaluate vaccine immunogenicity with OPKA
Opsonophagocytic killing assays (OPKA/OPA) and multiplex OPKA (MOPA) evaluate the ability of antibodies to opsonize bacteria, facilitating their destruction by immune cells. Unlike ELISAs, which quantify antibodies, opsonophagocytic assays measure their functionality — specifically, whether they trigger immune responses that kill bacteria. For vaccines targeting encapsulated bacteria like S. pneumoniae, OPKA data are especially vital […]