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Vaccine Immunogenicity

Learn How to Improve Immunogenicity Assay Accuracy with Antibody-Depleted Complement

Immunogenicity testing is central to vaccine development, helping researchers determine whether a vaccine candidate can elicit a protective immune response.

July 18, 2025

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9 min read

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Antibody Methods 3
Complement Biology 5
IVD & Clinical Assays 3
Vaccine Immunogenicity 6

Antibody Methods

Don’t waste your valuable sera samples!

The high analytical error rate in immunoassays is well documented, estimated to range from 0.4% to 4.0%. These errors generate misleading or even false results, and are caused in large part by interference from endogenous antibodies in sera.

October 23, 2020

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8 min read

Complement Biology

Antibody Depleted Human Complement: We’ve Scaled Up Our Process!

For decades Pel-Freez has been the largest US producer of rabbit blood fractions and rabbit complement. Our baby rabbit complement is used globally in serum bactericidal assays (SBA) and opsonophagocytic assays (OPA) with great success.

October 20, 2020

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7 min read

Antibody Methods

Tips for Antibody Purification

The process of antibody production, whether hybridoma or recombinant protein production in mammalian cells or bacteria, necessitates antibody isolation from other proteins present in the sample (cell lysate, medium, ascites fluid, sera, etc.).

July 21, 2020

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6 min read

Vaccine Immunogenicity

Understanding the Clinical Significance of Immunoglobulin Tests

Many people tend to have perennial respiratory infections, eczema, or allergies that cannot be diagnosed with routine tests, such as lymphocyte subsets, immunoglobulin series, and white blood cells. Testing the levels of the five types of immunoglobulins is also necessary.

July 11, 2020

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8 min read

Vaccine Immunogenicity

Understanding Immunoassay Development: Sourcing Reagents

Immunoassays are used in the detection and quantification of molecules that are of biological interest, based on the selectivity and specificity of certain antibody reagents.

July 11, 2020

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6 min read

Antibody Methods

The Future of Antibodies in Neuroscience

Antibodies, also known as immunoglobulins, are protective proteins that the body’s immune system produces in response to foreign substances (antigens).

July 5, 2020

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6 min read

Complement Biology

Facts of Rabbit Complement – Infograph

Antibodies, also known as immunoglobulins, are protective proteins that the body’s immune system produces in response to foreign substances (antigens).

July 3, 2020

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3 min read

IVD & Clinical Assays

Importance of Human Serum – Infograph

The human serum is a circulating carrier of exogenous and endogenous liquids in the blood. It allows substances to stick to the molecules within the serum and be buried within it. Here is the importance of human serum: